Pure short-chain glycerol fatty acid esters and glycerylic cyclocarbonic fatty acid esters as surface active and antimicrobial coagels protecting surfaces by promoting superhydrophilicity

R. Valentin (1) , M. Alignan , G. Giacinti (1) , F.N.R. Renaud (2) , B. Raymond , Z. Mouloungui

1 CAI - Chimie Agro-Industrielle
2 MATEIS - Matériaux, ingénierie et science [Villeurbanne]

Pure glycerol fatty acid esters and glycerylic cyclocarbonic fatty acid esters have an amphiphilic structure, giving these biomolecules a broad range of physico-chemical and biological properties. Physico-chemical properties depend on chain lengths, odd or even carbon numbers on the chain, and glyceryl or cyclocarbonic polar heads. The spectrum of melting-point values for these molecules is large. Surface-activity is very important and through determination of the critical aggregation concentration (CAC), some fatty-acid esters are considered as solvo-surfactant biomolecules. Coupling these self-aggregation and crystallization properties, superhydrophilic surfaces were obtained. An efficient durable water repellent coating of various metallic and polymeric surfaces was allowed. Moreover, these fatty acid esters promoting superhydrophilicity showed biological activity against Gram positive, Gram negative, and yeast-like micro-organisms. Such surfaces coated by self-assembled fatty acid esters in a stable coagel state present a novel solution to surface-contamination risks from pathogen proliferation. © 2011 Elsevier Inc.

Mots clés: article; unclassified drug; short chain glycerol fatty acid ester; glycerol derivative; glycerylic cyclocarbonic fatty acid ester; short chain fatty acid; fatty acid ester; Surface active agents; nonhuman; priority journal; Pseudomonas aeruginosa; minimum inhibitory concentration; superhydrophilicity; Staphylococcus aureus; Candida albicans; chemical composition; Water; Surface-Active Agents; Yeasts; Wettability; Structure-Activity Relationship; Gram-Positive Bacteria; Anti-Infective Agents; concentration (parameters); Fatty Acids; Gram-Negative Bacteria; surface property; crystallization; Enterococcus faecalis; Microorganisms; Glycerol; Esters; Critical aggregation concentration; Biomolecules; Coagels; Biological molecule; Chemical properties; Esterification; Escherichia coli; Agglomeration; gel; Super-hydrophilicity; hydrophilicity; material coating; Solvo-surfactants; melting point; Self-aggregation; Pure monoglycerides; Pure glycerol carbonate esters

Domaines: Matériaux

R. Valentin, M. Alignan, G. Giacinti, F.N.R. Renaud, B. Raymond, et al.. Pure short-chain glycerol fatty acid esters and glycerylic cyclocarbonic fatty acid esters as surface active and antimicrobial coagels protecting surfaces by promoting superhydrophilicity. Journal of Colloid and Interface Science, 2012, 365 (1), pp.280-288. ⟨10.1016/j.jcis.2011.09.010⟩. ⟨hal-01834905⟩