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Hepatitis A: an epidemiological survey in blood donors, France 2015 to 2017

Abstract : Since mid-2016, hepatitis A virus (HAV) outbreaks, involving predominantly men who have sex with men (MSM), have affected countries in Europe and overseas. In France, HAV screening of blood donations in 2017 revealed a HAV-RNA prevalence ca fivefold higher than during 2015-16 (4.42/106 vs 0.86/106; p = 0.0005). In 2017, despite a higher male-to-female ratio (5.5 vs 0.7) and the identification of MSM-associated outbreak strains, only one of 11 infected male donors self-reported being a MSM. Since mid-2016, outbreaks involving mainly men who have sex with men (MSM) have been reported in European countries and overseas [1-6]. The outbreaks were associated with three genotype IA hepatitis A virus (HAV) strains: VDR_521_2016, RIVM_HAV16-090 and V16-25801. In this study, we report epidemiological and clinical findings pertaining to HAV infected blood donors before and during the recent outbreak in France.
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Pierre Gallian, Valérie Barlet, Lina Mouna, Sylvie Gross, Sophie Lecam, et al.. Hepatitis A: an epidemiological survey in blood donors, France 2015 to 2017. Eurosurveillance, European Centre for Disease Prevention and Control, 2018, 23 (21), ⟨10.2807/1560-7917.ES.2018.23.21.1800237⟩. ⟨hal-01826305⟩

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