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Long-term visual and systemic prognoses of 83 cases of biopsy-proven sarcoid uveitis

Abstract : AIMS: To determine the long-term visual and systemic outcomes of uveitis patients with biopsy-proven sarcoidosis. METHODS: A retrospective study of biopsy-proven sarcoid uveitis, with a 3-year minimum follow-up, seen at Lyon University Hospital, between April 2004 and January 2016. RESULTS: A total of 83 patients were included, with a median age at onset of 52 (37-62) years and an unbalanced gender ratio (women 77.1%). Thirty-one patients had original systemic sarcoidosis in addition to ocular localisation, whereas 52 initially presented with isolated sarcoid uveitis. Among the latter, 7.7% (n=4) developed an extraocular disease after a median follow-up duration of 60 (44-110) months. The systemic spread in these patients included cutaneous sarcoids (n=2), arthritis (n=1) and multiple mononeuritis (n=1). Complete visual recovery was obtained for 60.2% of all patients and 89.2% had retrieved best-corrected visual acuity (BCVA) \\textgreater20/50 in both eyes. A unilateral loss of BCVA of worse than 20/200 was documented in two patients in the isolated sarcoid uveitis group. No patient suffered from bilateral severe visual impairment or blindness. Factors linked to a poor visual prognosis, defined by BCVA
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Submitted on : Friday, May 25, 2018 - 2:37:11 PM
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Cédric Rochepeau, Yvan Jamilloux, Sebastien Kerever, Camille Febvay, Laurent Perard, et al.. Long-term visual and systemic prognoses of 83 cases of biopsy-proven sarcoid uveitis. British Journal of Ophthalmology, BMJ Publishing Group, 2017, 101 (7), pp.856-861. ⟨10.1136/bjophthalmol-2016-309767⟩. ⟨hal-01799998⟩



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