PanGeneHome : A Web Interface to Analyze Microbial Pangenomes

Camille Loiseau , Victor Hatte , Charlotte Andrieu , Loic Barlet , Audric Cologne , Romain de Oliveira , Lionel Ferrato-Berberian , Hélène Gardon (1) , Damien Lauber , Mélanie Molinier , Stéphanie Monnerie , Kissi N 'Gou , Benjamin Penaud , Olivier Pereira , Justine Picarle , Amandine Septier , Antoine Mahul , Jean-Christophe Charvy (1) , François Enault (1)

1 LMGE - Laboratoire Microorganismes : Génome et Environnement

PanGeneHome is a web server dedicated to the analysis of available microbial pangenomes. For any prokaryotic taxon with at least three sequenced genomes, PanGeneHome provides (i) conservation level of genes, (ii) pangenome and core-genome curves, estimated pangenome size and other metrics, (iii) dendrograms based on gene content and average amino acid identity (AAI) for these genomes, and (iv) functional categories and metabolic pathways represented in the core, accessory and unique gene pools of the selected taxon. In addition, the results for these different analyses can be compared for any set of taxa. With the availability of 615 taxa, covering 182 species and 49 orders, PanGeneHome provides an easy way to get a glimpse on the pangenome of a microbial group of interest. The server and its documentation are available at http://pangenehome.lmge.uca.fr.

Mots clés: Prokaryote pangenome; Comparative genomics; Bioinformatics; Web site

Domaines: Bio-Informatique, Biologie Systémique [q-bio.QM]

Camille Loiseau, Victor Hatte, Charlotte Andrieu, Loic Barlet, Audric Cologne, et al.. PanGeneHome : A Web Interface to Analyze Microbial Pangenomes. Journal of Bioinformatics, Computational and Systems Biology, 2017. ⟨hal-01786921⟩