Characterization of the power dependency regimes of inhomogeneous Magnetization Transfer (ihMT)

Samira Mchinda , Gopal Varma , Valentin H Prevost , Arnaud Le Troter (1) , Maxime Guye (1) , Jean Pelletier (1) , Jean-Philippe Ranjeva (1) , David C Alsop , Guillaume Duhamel (1) , Olivier M Girard

1 CRMBM - Centre de résonance magnétique biologique et médicale

Inhomogeneous magnetization transfer (ihMT) is a new MRI technique that shows promise for myelin imaging. A significant boost of the ihMT signal intensity is achievable when using a concentrated energy deposition scheme. Here we characterized the power dependency of ihMT for various energy deposition schemes (distributed vs. concentrated RF) and we identified distinct regimes with linear, sub-linear and saturated B1 dependency. This has a strong impact on the ihMT response to variable sequence configurations and on the most suitable conditions for different field strengths, e.g. to enhance sensitivity or provide immunity to B1^\textrm+ inhomogeneities.

Domaines: Imagerie; Imagerie médicale

Samira Mchinda, Gopal Varma, Valentin H Prevost, Arnaud Le Troter, Maxime Guye, et al.. Characterization of the power dependency regimes of inhomogeneous Magnetization Transfer (ihMT). Proc. Intl. Soc. Mag. Reson. Med. 25, 2017, Unknown, Unknown Region. pp.3763. ⟨hal-01784668⟩