3D static elastography at the micrometer scale using Full Field OCT

Abstract : Full-Field OCT (FF-OCT) is able to image biological tissues in 3D with micrometer resolution. In this study we add elastographic contrast to the FF-OCT modality. By combining FF-OCT with elastography, we create a “virtual palpation” map at the micrometer scale. We present here a proof of concept on multi-layer phantoms and preliminary results on ex vivo biological samples such as porcine cornea, human breast tissues and rat heart. The 3D digital volume correlation that is used in connection with the 3D stack of images allows to access to the full 3D strain tensor and to reveal stiffness anisotropy.
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https://hal.archives-ouvertes.fr/hal-01709281
Contributor : Stéphane Roux <>
Submitted on : Wednesday, February 14, 2018 - 6:00:10 PM
Last modification on : Friday, July 5, 2019 - 1:27:25 AM

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Amir Nahas, Morgane Bauer, Stéphane Roux, Albert-Claude Boccara. 3D static elastography at the micrometer scale using Full Field OCT. Biomedical optics express, Optical Society - SOA Publishing, 2013, 4 (10), pp.2138-2149. ⟨https://www.osapublishing.org⟩. ⟨10.1364/BOE.4.002138⟩. ⟨hal-01709281⟩

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