Allosteric nanobodies uncovered a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.

Pauline Scholler (1, 2) , Damien Nevoltris (3, 2) , Dimitri de Bundel (1) , Simon Bossi (4) , David Moreno-Delgado (1) , Xavier Rovira (1) , Driss El Moustaine (1) , Michaël Mathieu (1) , Emilie Blanc (1) , Heather Mclean (4) , Elodie Dupuis (2) , Gérard Mathis (2) , Eric Trinquet (2) , Hervé Daniel (4) , Emmanuel Valjent (1) , Daniel Baty (3) , Patrick Chames (3) , Philippe Rondard (1) , Jean-Philippe Pin (1)

1 UM - Université de Montpellier
2 Cisbio Bioassays
3 CRCM - Centre de Recherche en Cancérologie de Marseille
4 NeuroPSI - Institut des Neurosciences Paris-Saclay

Domaines: Sciences du Vivant [q-bio]

Pauline Scholler, Damien Nevoltris, Dimitri de Bundel, Simon Bossi, David Moreno-Delgado, et al.. Allosteric nanobodies uncovered a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation.. Nature Communications, 2017. ⟨hal-01672805v1⟩