Cortical bone elasticity measured by resonant ultrasound spectroscopy is not altered by defatting and synchrotron X-ray imaging

X. Cai (1) , L. Peralta (1) , A. Giron (1) , L. Helfen (2, 3) , Cécile Olivier (4, 3) , Françoise Peyrin (4) , Pascal Laugier (1) , Q. Grimal (1, 3, 4)

1 LIB - Laboratoire d'Imagerie Biomédicale [Paris]
2 Karlsruhe Inst Technol, Inst Photon Sci & Synchrotron Radiat, Hermann von Helmholtz Pl 1, D-76344 Eggenstein Leopoldshafen, Germany
3 ESRF - European Synchrotron Radiation Facility
4 Imagerie Tomographique et Radiothérapie

In the study of mechanical properties of human bone, specimens may be defatted before experiments to prevent contamination and the risk of infections. High energy synchrotron radiation micro-computed tomography (SR-μCT) is a popular technique to study bone microstructure. However, little is known about the effects of defatting or irradiation during SR-μCT imaging on different elastic coefficients including shear and longitudinal moduli in different anatomical directions. In this work, these effects are evaluated on a set of 24 samples using resonant ultrasound spectroscopy (RUS), which allows one to accurately measure the complete set of elastic coefficients of cortical bone non destructively. The results show that defatting with diethylether and methanol and irradiation up to 2.5kGy has no detectable effect on any of the elastic coefficients of human cortical bone.

Mots clés: Elasticity; Cortical bone; Irradiation; Defatting; Resonant ultrasound spectroscopy

Domaines: Imagerie; Traitement du signal et de l'image [eess.SP]

X. Cai, L. Peralta, A. Giron, L. Helfen, Cécile Olivier, et al.. Cortical bone elasticity measured by resonant ultrasound spectroscopy is not altered by defatting and synchrotron X-ray imaging. Journal of the mechanical behavior of biomedical materials, 2017, 72, pp.241 - 245. ⟨10.1016/j.jmbbm.2017.05.012⟩. ⟨hal-01597533⟩