Wide-field optical coherence tomography: Imaging of biological tissues at 1220 nm

E. Bordenave , Emmanuel Abraham (1) , Gediminas Jonusauskas (1) , N. Tsurumachi , J. Oberle (1) , C. Rulliere (1) , P. E. Minot , M. Lassegues (2) , J. E. S. Bazeille

1 CPMOH - Centre de physique moléculaire optique et hertzienne
2 FDRC - Facteurs de Défense et de Régulation Cellulaire

A two-dimensional optical coherence tomography technique has been developed in order to obtain multiple longitudinal slices of a biological sample directly, in a single Z-scan. The system is based on a femtosecond Cr⁴⁺:Forsterite laser and an infrared camera for wide-field imaging of the sample with a depth resolution of 9 micrometers . With this imaging apparatus, we investigated biological tissues such as human skin, human tooth and a mouse ear to observe the different constitutive tissues of the samples.

Domaines: Physique [physics]

E. Bordenave, Emmanuel Abraham, Gediminas Jonusauskas, N. Tsurumachi, J. Oberle, et al.. Wide-field optical coherence tomography: Imaging of biological tissues at 1220 nm. AnderssonEngels, S. and Kaschke, M. F. European Conferences on biomedical optics, Jun 2001, Munich, Germany. Proceedings of SPIE, the International Society for Optical Engineering, 4431, pp.30-37, 2001, Photon Migration, Optical Coherence Tomography, and Microscopy, ⟨10.1117/12.447397⟩. ⟨hal-01550666⟩