Hydrodynamic interactions in DNA thermophoresis

Abstract : We theoretically study the molecular-weight dependence of DNA thermophoresis, which arises from mutual advection of the n repeat units of the molecular chain. As a main result we find that the dominant driving forces, i.e., the thermally induced permittivity gradient and the electrolyte Seebeck effect, result in characteristic hydrodynamic screening. In comparison with recent experimental data on single-stranded DNA (2 ≤ n ≤ 80), our theory quantitatively describes the increase of the drift velocity up to n = 30; the slowing-down of longer molecules is well accounted for by a simple model for counterion condensation. It turns out that thermophoresis may change sign as a function of n: For an appropriate choice of the salt-specific Seebeck coefficient, short molecules move to the cold and long ones to the hot; this could be used for separating DNA by molecular weight.
Type de document :
Article dans une revue
Soft Matter, Royal Society of Chemistry, 2018, 14 (5), pp.848-852. 〈10.1039/c7sm01317e〉
Liste complète des métadonnées

Littérature citée [6 références]  Voir  Masquer  Télécharger

https://hal.archives-ouvertes.fr/hal-01549636
Contributeur : Alois Würger <>
Soumis le : mercredi 28 juin 2017 - 22:29:06
Dernière modification le : vendredi 2 février 2018 - 17:43:02
Document(s) archivé(s) le : jeudi 18 janvier 2018 - 01:21:30

Fichiers

hd.pdf
Fichiers produits par l'(les) auteur(s)

Licence


Distributed under a Creative Commons Paternité 4.0 International License

Identifiants

Collections

Citation

Aboubakry Ly, Aloïs Würger. Hydrodynamic interactions in DNA thermophoresis. Soft Matter, Royal Society of Chemistry, 2018, 14 (5), pp.848-852. 〈10.1039/c7sm01317e〉. 〈hal-01549636〉

Partager

Métriques

Consultations de la notice

100

Téléchargements de fichiers

34