Circadian Control of Antibacterial Immunity: Findings from Animal Models

Landry L. Tsoumtsa (1) , Cedric Torre (1) , Eric Ghigo (1)

1 URMITE - Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes

Most of the biological functions, including the immune system, are linked to circadian rhythms in living organisms. Changes occurring to biological parameters as the result of these circadian rhythms can therefore affect the outcome of a disease. For decades, model organisms have proven to be a great tool to understanding biological mechanisms such as circadian cycle and immunity. In this review, we created an inventory of the use of model organisms in order to decipher the relation between circadian rhythms and antibacterial immunity.

Mots clés: Antibacterial; Bacteria; Circadian; Drosophila; Mice; Chrono-immunology

Domaines: Immunité innée

Landry L. Tsoumtsa, Cedric Torre, Eric Ghigo. Circadian Control of Antibacterial Immunity: Findings from Animal Models. Frontiers in Cellular and Infection Microbiology, 2016, 6, pp.54. ⟨10.3389/fcimb.2016.00054⟩. ⟨hal-01458370⟩