Phospholipid–silica mesophases formed in hydroalcoholic solution as precursors of mesoporous silica

Nadia Toumi (1, 2) , Sylvie Begu (1) , Thomas Cacciaguerra (1) , Anne Galarneau (1) , Thierry Azais (3) , Abdelkader Bengueddach (2) , Francesco Di Renzo (1)

1 ICGM - Institut Charles Gerhardt Montpellier - Institut de Chimie Moléculaire et des Matériaux de Montpellier
2 Université d'Oran 1, Mat Chem Lab, Oran Es Senia, Algeria
3 SMiLES - Spectroscopie, Modélisation, Interfaces pour L'Environnement et la Santé

Phosphatidylcholine isotropic mesophases are easily formed by membrane fusion in hydroalcoholic solution in the presence of condensating silica. The transformation of lamellar bilayers into a sponge phase proceeds with the increase of the concentration of ethanol until a monodispersed mesoporous silica with surface area 800 m2 g-1 can be formed by calcination. Natural impurities of lecithin favour the formation of the sponge phase.

Domaines: Matériaux

Nadia Toumi, Sylvie Begu, Thomas Cacciaguerra, Anne Galarneau, Thierry Azais, et al.. Phospholipid–silica mesophases formed in hydroalcoholic solution as precursors of mesoporous silica. New Journal of Chemistry, 2016, 40 (5), pp.4314-4318. ⟨10.1039/c5nj03563e⟩. ⟨hal-01318863⟩