In-vivo free-breathing DTI & IVIM of the whole human heart using a real-time slice-followed SE-EPI navigator-based sequence: a reproducibility study in healthy volunteers

Kévin Moulin (1, 2) , Pierre Croisille (1, 3) , Thorsten Feiweier (4) , Bénédicte Delattre (5) , Hongjiang Wei (5) , Benjamin Robert (2) , Olivier Beuf (1) , Magalie Viallon (3, 1)

1 RMN et optique : De la mesure au biomarqueur
2 Siemens Healthcare [France]
3 Service de Radiologie [CHU Saint-Etienne]
4 Siemens AG Healthcare Sector, Erlangen
5 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé

Purpose:In-vivo cardiac diffusion analysis using either the Intra-Voxel Incoherent Motion (IVIM) model or the Diffusion Tensor Imaging (DTI) model shows promise to provide new insights into heart pathologies. However, due to the combined challenge of respiratory and heart motion (1, 2), currently proposed acquisition methods are quite demanding for unhealthy patients. In this study, we propose to use the motion information provided by a navigator to prospectively update in real time the position of the diffusion-weighted slices in order to offer an efficient free-breathing strategy for rapid and efficient cardiac diffusion acquisition using a single-shot Spin-Echo EPI sequence (SE-EPI)

Domaines: Imagerie

Kévin Moulin, Pierre Croisille, Thorsten Feiweier, Bénédicte Delattre, Hongjiang Wei, et al.. In-vivo free-breathing DTI & IVIM of the whole human heart using a real-time slice-followed SE-EPI navigator-based sequence: a reproducibility study in healthy volunteers. ISMRM 23rd Annual Meeting & Exhibition, May 2015, Toronto, Canada. ⟨hal-01288460⟩