Comparison of regularized phase retrieval algorithms for x-ray phase contrast tomography - application on experimental data

Loriane Weber (1, 2) , Max Langer (1, 2, 3) , Peter Cloetens (1) , Francoise Peyrin (1, 2)

1 ESRF - European Synchrotron Radiation Facility
2 CREATIS - Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé
3 Imagerie Tomographique et Radiothérapie

In this work, different regularization methods were applied to phase retrieval in phase contrast micro-tomography of Skelite scaffolds seeded with bone forming cells. The use of phase tomography allows the quantification of both mineralized and soft tissue, unlike with classical X-ray micro-computed tomography (μCT). Further, the application of a priori terms that allow for heterogeneous objects enabled the quantification cells trapped in the pre-bone matrix.

Domaines: Imagerie

Loriane Weber, Max Langer, Peter Cloetens, Francoise Peyrin. Comparison of regularized phase retrieval algorithms for x-ray phase contrast tomography - application on experimental data. 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), Apr 2015, New-York, United States. ⟨hal-01274021⟩