Theoretical and practical interest in UHPLC technology for 2D-LC

Morgan Sarrut 1 Gérard Crétier 1 Sabine Heinisch 1, *
* Corresponding author
Abstract : Comprehensive two-dimensional liquid chromatography (LC x LC) has significantly improved the separation power of LC for complex samples. Our review opens with theoretical considerations about online LC x LC in order to explain why ultra-high-pressure LC (UHPLC) and more specifically, hightemperature (HT)-UHPLC are very convenient in the second dimension. We present some recent applications involving UHPLC in LC x LC. They cover a wide range of analytical fields, such as food analysis, life sciences, bioenergy and polymers
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Submitted on : Tuesday, November 17, 2015 - 6:10:14 PM
Last modification on : Monday, December 3, 2018 - 12:32:02 PM

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Morgan Sarrut, Gérard Crétier, Sabine Heinisch. Theoretical and practical interest in UHPLC technology for 2D-LC. Trends in Analytical Chemistry, Elsevier, 2014, 63, pp.104-112. ⟨10.1016/j.trac.2014.08.005⟩. ⟨hal-01230120⟩

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