Amoeboid motion in confined geometry

Hao Wu 1 M. Thiébaud 1 W.-F. Hu 2 A. Farutin 1 S. Rafaï 1 M.-C. Lai 2 P. Peyla 1 C. Misbah 1
1 LIPHY-DYFCOM
LIPhy - Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères]
Abstract : Many eukaryotic cells undergo frequent shape changes (described as amoeboid motion) that enable them to move forward. We investigate the effect of confinement on a minimal model of amoeboid swimmer. A complex picture emerges: (i) The swimmer's nature (i.e., either pusher or puller) can be modified by confinement, thus suggesting that this is not an intrinsic property of the swimmer. This swimming nature transition stems from intricate internal degrees of freedom of membrane deformation. (ii) The swimming speed might increase with increasing confinement before decreasing again for stronger confinements. (iii) A straight amoeoboid swimmer's trajectory in the channel can become unstable, and ample lateral excursions of the swimmer prevail. This happens for both pusher- and puller-type swimmers. For weak confinement, these excursions are symmetric, while they become asymmetric at stronger confinement, whereby the swimmer is located closer to one of the two walls. In this study, we combine numerical and theoretical analyses.
Complete list of metadatas

Cited literature [21 references]  Display  Hide  Download

https://hal.archives-ouvertes.fr/hal-01230092
Contributor : Salima Rafaï <>
Submitted on : Tuesday, November 17, 2015 - 5:13:36 PM
Last modification on : Tuesday, September 11, 2018 - 9:24:02 AM
Long-term archiving on : Thursday, February 18, 2016 - 3:02:54 PM

Files

HAOoct.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Hao Wu, M. Thiébaud, W.-F. Hu, A. Farutin, S. Rafaï, et al.. Amoeboid motion in confined geometry. Physical Review E : Statistical, Nonlinear, and Soft Matter Physics, American Physical Society, 2015, 92 (5), ⟨10.1103/PhysRevE.92.050701⟩. ⟨hal-01230092⟩

Share

Metrics

Record views

185

Files downloads

349