Antioxidant activities of a polyglucuronic acid sodium salt obtained from TEMPO-mediated oxidation of xanthan.

Abstract : A xanthouronic acid sodium salt called xanthouronan was produced from xanthan by regioselective oxidation with NaOCl/NaBr using 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO) as catalyst. The efficiency of the one pot TEMPO-mediated oxidation was confirmed by HPAEC-PAD, 13C NMR, and FT-IR. The oxidation degree was close to 98% and the mass yield of this new polyglucuronic acid was higher than 90% (w/w). The macromolecular characterization of xanthouronan using SEC-MALLS showed a molecular size reduced by a third due to the oxidation treatment and the degree of polymerization (DP) of the xanthouronan form was about 665. The evaluation of the enzymatic degradation of this C-6 carboxylated xanthan by various polysaccharide hydrolases and one polysaccharide lyase showed its high resistant to biodegradation. The antioxidant activity of xanthouronan was also tested by using the 2,2′-diphenyl-1-picrylhydrazyle (DPPH) and hydroxyl radical procedures. At 1 g/L, xanthouronan presented 75% of the ascorbic acid antioxidant activity.
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https://hal.archives-ouvertes.fr/hal-01206750
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Submitted on : Tuesday, September 29, 2015 - 3:39:36 PM
Last modification on : Tuesday, June 11, 2019 - 2:38:01 PM

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Cédric Delattre, Guillaume Pierre, Christine Gardarin, Mounir Traïkia, Redouan Elboutachfaiti, et al.. Antioxidant activities of a polyglucuronic acid sodium salt obtained from TEMPO-mediated oxidation of xanthan.. Carbohydrate Polymers, Elsevier, 2015, 116, pp.34-41. ⟨10.1016/j.carbpol.2014.04.054⟩. ⟨hal-01206750⟩

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