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Article Dans Une Revue Chemical Communications Année : 2015

Methylene blue phosphoramidite for DNA labelling

Résumé

We report the first synthesis of a methylene blue (MB) phosphoramidite derivative suitable for DNA solid-phase synthesis. The electrochemical and optical properties of the resulting MB modified oligonucleotides were confirmed. This new molecule is an important breakthrough in the design of new probes labelled with MB.
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Dates et versions

hal-01187184 , version 1 (26-08-2015)

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Gabriel de Crozals, Carole Farre, Monique Sigaud, Philippe Fortgang, Corinne Sanglar, et al.. Methylene blue phosphoramidite for DNA labelling. Chemical Communications, 2015, 51 (21), pp.4458-4461. ⟨10.1039/c4cc10164b⟩. ⟨hal-01187184⟩
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