Carbon Dioxide Reduction to Methylamines under Metal-Free Conditions

Enguerrand Blondiaux (1) , Jacky Pouessel (1) , Thibault Cantat (1)

1 LCMCE - Laboratoire de Chimie Moléculaire et de Catalyse pour l'Energie (ex LCCEF)

The first metal-free catalysts are reported for the methylation of amines with carbon dioxide. Proazaphosphatrane superbases prove to be highly active catalysts in the reductive functionalization of CO2, in the presence of hydroboranes. The new methodology enables the methylation of NH bonds in a wide variety of amines, including secondary amines, with increased chemoselectivity.

Mots clés: amines; boranes; carbon dioxide; organocatalysis; reduction

Domaines: Chimie de coordination

Enguerrand Blondiaux, Jacky Pouessel, Thibault Cantat. Carbon Dioxide Reduction to Methylamines under Metal-Free Conditions. Angewandte Chemie International Edition, 2014, 53 (45), pp.12186-12190. ⟨10.1002/anie.201407357⟩. ⟨hal-01157654⟩