Skip to Main content Skip to Navigation
Journal articles

A Sensitive Zinc-Activated 129Xe MRI Probe

Abstract : Xenon capsule: A smart 129Xe NMR-based sensor of Zn2+ ions for magnetic resonance imaging (MRI) is proposed. The resonance frequency of xenon encapsulated in a cryptophane that bears a nitrilotriacetic ligand moiety varies when Zn2+ ions are present in solution (see picture). With hyper-polarized gas, such a construct enables detection of 100 nM zinc in one xenon batch, a threshold 300 times lower than achieved with gadolinium chelates.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-01117150
Contributor : Pourlc Déposant <>
Submitted on : Monday, February 16, 2015 - 2:46:38 PM
Last modification on : Tuesday, November 3, 2020 - 9:50:04 AM

Links full text

Identifiers

Citation

Naoko Kotera, Nawal Tassali, Estelle Léonce, Céline Boutin, Patrick Berthault, et al.. A Sensitive Zinc-Activated 129Xe MRI Probe. Angewandte Chemie International Edition, Wiley-VCH Verlag, 2012, 51 (17), pp.4100-4103. ⟨10.1002/anie.201109194⟩. ⟨hal-01117150⟩

Share

Metrics

Record views

180