MOF functionalization with short peptides for asymmetric applications

J. Canivet (1) , J. Bonnefoy (1) , D. Farrusseng (1)

1 IRCELYON - Institut de recherches sur la catalyse et l'environnement de Lyon

Grafting of chiral species such as amino-acids inside MOF cavities allows designing bio-functional materials and the covalent post-synthetic modification is a tool of choice to increase the sophistication degree in porous materials. We will present the synthesis and applications of amino acids-functionalized MOF following a methodology tightly integrating molecular modeling and experimental work. Solid phase peptide coupling strategy is applied in order to immobilize short peptides inside amino-functionalized MOF frameworks. A new method allows reaction times shortening, from days to minutes, and higher grafting yields, up to 60% of amino groups converted. Furthermore dipeptide-functionalized MOFs act as platforms for the design of chiral organometallics confined inside MOF nanospace, efficient in heterogeneous asymmetric catalysis.

Domaines: Catalyse; Environnement et Société

J. Canivet, J. Bonnefoy, D. Farrusseng. MOF functionalization with short peptides for asymmetric applications. 2nd MOF Young Investigator Symposium, Sep 2014, Kyoto, Japan. ⟨hal-01111140⟩