All-organic micromechanical systems integrating specific molecular recognition

C. Ayela (1) , G. Dubourg (1) , C. Pellet (1) , Karsten Haupt (2)

1 IMS - Laboratoire de l'intégration, du matériau au système
2 GEC - Génie Enzymatique et Cellulaire

Cantilever-type all-organic microelectromechanical systems based on molecularly imprinted polymers for specific analyte recognition are used as chemical sensors. They are produced by a simple spray-coating-shadow-masking process. Analyte binding to the cantilever generates a measurable change in its resonance frequency. This allows label-free detection by direct mass sensing of low-molecular-weight analytes at nanomolar concentrations.

Domaines: Chimie; Sciences du Vivant [q-bio]

C. Ayela, G. Dubourg, C. Pellet, Karsten Haupt. All-organic micromechanical systems integrating specific molecular recognition: A new generation of chemical sensors. Advanced Materials, 2014, 26, pp.5876-5879. ⟨10.1002/adma.201401088⟩. ⟨hal-01344573⟩