Cerium(IV) ammonium nitrate mediated three-component α-allylation of imine surrogates.

Mathieu Bekkaye (1) , Géraldine Masson (1)

1 ICSN - Institut de Chimie des Substances Naturelles

A general and practical CAN-mediated oxidative radical α-coupling reaction of various imine surrogates with allylsilanes has been described. This multicomponent process affords β-allylated α-carbamido ethers as stable imine precursors in respectable yields under mild conditions.

Domaines: Chimie organique

Mathieu Bekkaye, Géraldine Masson. Cerium(IV) ammonium nitrate mediated three-component α-allylation of imine surrogates.. Organic Letters, 2014, 16 (5), pp.1510-3. ⟨10.1021/ol5004143⟩. ⟨hal-00986317⟩