Challenges in recording and stimulation of living neural network based on original micro-electrode array (MEA) developments

Myline Cottance (1) , Sebastien Nazeer (1) , L. Rousseau (1) , Gaelle Bazin Lissorgues (1) , Sébastien Joucla (2) , Blaise Yvert (2) , Noëlle Lewis (3) , Yannick Bornat (3) , S. Renaud (3)

1 ESYCOM - Electronique, Systèmes de communication et Microsystèmes
2 INCIA - Institut de Neurosciences cognitives et intégratives d'Aquitaine
3 IMS - Laboratoire de l'intégration, du matériau au système

Recent research in micro-manufacturing together with new technologies in bioelectronics can lead to neuroscience applications to explore the properties of neural networks. Micro Electrode Arrays correspond to a well suited tool to either stimulate or record large populations of cultured cells and tissues. Based on existing state-of-the-art MEAs, the paper describes original developments to improve either recording or stimulation of neural networks, focusing on action potential discrimination.

Domaines: Electronique

Myline Cottance, Sebastien Nazeer, L. Rousseau, Gaelle Bazin Lissorgues, Sébastien Joucla, et al.. Challenges in recording and stimulation of living neural network based on original micro-electrode array (MEA) developments. 2013 IEEE 11th International Conference on New Circuits and Systems (NEWCAS), Jun 2013, France. pp.1-4, ⟨10.1109/NEWCAS.2013.6573645⟩. ⟨hal-00980781⟩