Wired Pyrroloquinoline Quinone Soluble Glucose Dehydrogenase Enzyme Electrodes Operating at Unprecedented Low Redox Potential

Victoria Flexer (1) , Nicolas Mano (1)

1 CRPP - Centre de recherches Paul Pascal

We report unprecedented high current densities for the enzymatic oxidation of glucose already at 0 V versus Ag/AgCl. The modified electrodes were made by assembling pyrroloquinoline quinone (PQQ)-soluble glucose dehydrogenase (PQQ-sGDH) from Acinetobacter calcoaceticus with osmium-based redox polymers and a crosslinker. Both redox mediators are made of a poly(4-vinylpyridine) (PVP) polymer with Os complexes tethered to the polymer backbone via long C chains, giving the Os complexes flexibility and mobility inside the redox hydrogels. Current densities larger than 1 mA cm−2 were measured already below 0 V with a plateau value of 4.4 mA cm−2.....

Domaines: Catalyse

Victoria Flexer, Nicolas Mano. Wired Pyrroloquinoline Quinone Soluble Glucose Dehydrogenase Enzyme Electrodes Operating at Unprecedented Low Redox Potential. Analytical Chemistry, 2014, 86 (5), pp. 2465-2473. ⟨10.1021/ac403334w⟩. ⟨hal-00955388⟩