Comparative analysis of phylogenetic profiles for the enzymatic characterization of fungal group

Cécile Pereira 1 Jérôme Azé 2, 3 Alain Denise 2, 3, 4 Christine Drevet 4 Christine Froidevaux 2, 3 Philippe Silar 4 Olivier Lespinet 4
3 AMIB - Algorithms and Models for Integrative Biology
CNRS - Centre National de la Recherche Scientifique : UMR8623, X - École polytechnique, Inria Saclay - Ile de France, UP11 - Université Paris-Sud - Paris 11, LRI - Laboratoire de Recherche en Informatique, LIX - Laboratoire d'informatique de l'École polytechnique [Palaiseau]
Abstract : We try to characterize the evolutionary origin of the enzymatic repertoire of different fungal groups. The characteristics for each of the groups studied are determined through the application of data mining method on enzyme profiles previously determined by comparative genomics. Through the presentation of results for taxonomic groups Agaricomycetes and Pezizomycota, we show that the application of supervised learning methods is effective in extracting information from phylogenetic profiles. We extract specific enzyme activities combinations for each taxonomic groups covered by our analysis. Our approach also enables us to highlight the existence of probable horizontal gene transfers.
Type de document :
Communication dans un congrès
JOBIM 2013 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2013, Toulouse, France. à paraître, 2013
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https://hal.archives-ouvertes.fr/hal-00842021
Contributeur : Alain Denise <>
Soumis le : samedi 6 juillet 2013 - 11:35:06
Dernière modification le : jeudi 10 mai 2018 - 02:06:05

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  • HAL Id : hal-00842021, version 1

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Cécile Pereira, Jérôme Azé, Alain Denise, Christine Drevet, Christine Froidevaux, et al.. Comparative analysis of phylogenetic profiles for the enzymatic characterization of fungal group. JOBIM 2013 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2013, Toulouse, France. à paraître, 2013. 〈hal-00842021〉

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