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Comparative analysis of phylogenetic profiles for the enzymatic characterization of fungal group

Cécile Pereira 1 Jérôme Azé 2, 3 Alain Denise 2, 3, 4 Christine Drevet 4 Christine Froidevaux 2, 3 Philippe Silar 4 Olivier Lespinet 4
3 AMIB - Algorithms and Models for Integrative Biology
LIX - Laboratoire d'informatique de l'École polytechnique [Palaiseau], LRI - Laboratoire de Recherche en Informatique, UP11 - Université Paris-Sud - Paris 11, Inria Saclay - Ile de France
Abstract : We try to characterize the evolutionary origin of the enzymatic repertoire of different fungal groups. The characteristics for each of the groups studied are determined through the application of data mining method on enzyme profiles previously determined by comparative genomics. Through the presentation of results for taxonomic groups Agaricomycetes and Pezizomycota, we show that the application of supervised learning methods is effective in extracting information from phylogenetic profiles. We extract specific enzyme activities combinations for each taxonomic groups covered by our analysis. Our approach also enables us to highlight the existence of probable horizontal gene transfers.
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https://hal.archives-ouvertes.fr/hal-00842021
Contributor : Alain Denise <>
Submitted on : Saturday, July 6, 2013 - 11:35:06 AM
Last modification on : Tuesday, April 21, 2020 - 1:07:04 AM

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Cécile Pereira, Jérôme Azé, Alain Denise, Christine Drevet, Christine Froidevaux, et al.. Comparative analysis of phylogenetic profiles for the enzymatic characterization of fungal group. JOBIM 2013 - Journées Ouvertes en Biologie, Informatique et Mathématiques, Jul 2013, Toulouse, France. à paraître. ⟨hal-00842021⟩

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