Is total community viral load a robust predictive marker of the efficacy of the TasP strategy?

Sandrine Henard , Eliette Jeanmaire , Yohan Nguyen , Yazdan Yazdanpanah (1, 2) , Antoine Cheret , Bruno Hoen (3, 4) , David Rey , Alice Borel , Pascal Chavanet (5) , Thierry May (6) , Christian Rabaud , Non Renseigné

1 ATIP-Avenir Inserm - Modélisation, Aide à la Décision, et Coût-Efficacité en Maladies Infectieuses
2 Service de maladies infectieuses et tropicales
3 LCE - Laboratoire Chrono-environnement (UMR 6249)
4 Service des maladies infectieuses et tropicales
5 Service de Maladies Infectieuses et Tropicales [CHU Dijon]
6 Service des Maladies Infectieuses et Tropicales [CHRU Nancy]

A mild but significant association between a decrease in the total community viral load (CVL) and a decrease in the number of new HIV diagnoses was observed between 2005 and 2010 in the population of northern and eastern France. This result suggests that CVL could be used as robust marker of the efficacy of the "Treatment as Prevention" strategy, and it may even be stronger if a large number of undiagnosed patients and early HIV infection cases indicated by extend screening are included in the CVL measurement.

Domaines: Pétrographie; Sciences du Vivant [q-bio]

Sandrine Henard, Eliette Jeanmaire, Yohan Nguyen, Yazdan Yazdanpanah, Antoine Cheret, et al.. Is total community viral load a robust predictive marker of the efficacy of the TasP strategy?. Journal of Acquired Immune Deficiency Syndromes - JAIDS, 2012, 61 (3), pp.400-2. ⟨10.1097/QAI.0b013e318263a111⟩. ⟨hal-00825445⟩