Synthesis of antibacterial surfaces by plasma grafting of zinc oxide based nanocomposites onto polypropylene
Résumé
Antibacterial polymer surfaces were designed using ZnO nanoparticles as a bactericide. Mineral encapsu- lated nanoparticles were grafted onto activated polymer surfaces through their shells. Polypropylene (PP) surfaces were treated using an innovative process coupling core-shell technology and plasma grafting, well-known techniques commonly used to obtain active surfaces for biomedical applications. First, ZnO nanoparticles were encapsulated by (co)polymers: poly(acrylic acid) (PAA) or a poly(methyl meth- acrylate-co-methacrylic acid) copolymer [P(MMA-MA)]. Second, PP substrates were activated using plasma treatment. Finally, plasma-treated surfaces were immersed in solutions containing the encapsu- lated nanoparticles dispersed in an organic solvent and allowed to graft onto it. The presence of nanopar- ticles on the substrates was demonstrated using Fourier-Transform Infrared Spectroscopy (FTIR) analysis, Scanning Electron Microspcopy (SEM)/Energy-Dispersive X-ray (EDX), and Atomic Force Microscopy (AFM) studies. Indeed, the ZnO-functionalized substrates exhibited an antibacterial response in Esche- richia coli adhesion tests. Moreover, this study revealed that, surprisingly, native ZnO nanoparticles with- out any previous functionalization could be directly grafted onto polymeric surfaces through plasma activation. The antibacterial activity of the resulting sample was shown to be comparable to that of the other samples.