Analytical Microsystems for Biomedical and Environmental Applications

Abstract : wo types of analytical microsystems for the detection of species of interest in biomedical diagnosis and in environmental monitoring are specifically described in this paper. We describe a novel device that will measure whole blood concentration of D-dimer, a recognized biomarker of increased blood clotting activity and that will then offer opportunity to use the test in the point of care setting. The device combines innovation in antibody bio-engineering for high specificity immunoassay-based diagnostics and nano/micro engineered impedimetric analysis electrodes incorporating a biocompatible polymer substrate with development of a disposable microfluidic manifold, enabling diagnostics at the point-of-first-contact. The feasibility of a generic microsytem integrating a microfluidic system of concentration and a module of electrochemical detection is demonstrated for the four metals of the European directive (DCE 2000/60/EC) for the quality of water resource: cadmium, mercury, lead and nickel.
Type de document :
Article dans une revue
Biocybernetics and Biomedical Engineering, 2011, 31 (4), pp.3-16
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Soumis le : mardi 9 avril 2013 - 17:10:42
Dernière modification le : jeudi 8 février 2018 - 11:10:19


  • HAL Id : hal-00809740, version 1



Nicole Jaffrezic-Renault, Abdelhamid Errachid. Analytical Microsystems for Biomedical and Environmental Applications. Biocybernetics and Biomedical Engineering, 2011, 31 (4), pp.3-16. 〈hal-00809740〉



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