Ruthenium(II)-catalyzed selective monoarylation in water and sequential functionalisations of C-H bonds.

Percia Beatrice Arockiam (1) , Cédric Fischmeister (1) , Christian Bruneau (1) , Pierre H. Dixneuf (1)

1 ISCR - Institut des Sciences Chimiques de Rennes

The ruthenium(II)-phosphine catalyst RuCl2(PPh3)(p-cymene) operating water selectively leads to ortho monoarylation, with arylchlorides and heteroarylhalides, of functional arenes. Further catalytic heteroarylation with Ru(OAc)(2)(p-cymene) in water produces mixed bifunctional derivatives.

Mots clés: DIRECT ORTHO ARYLATION; CATALYTIC FUNCTIONALIZATION; ORTHO-ALKENYLATION; CARBON-HYDROGEN; ACTIVATION; CARBOXYLATE; BENZAMIDES; MECHANISM; CLEAVAGE; ALKENES

Domaines: Autre

Percia Beatrice Arockiam, Cédric Fischmeister, Christian Bruneau, Pierre H. Dixneuf. Ruthenium(II)-catalyzed selective monoarylation in water and sequential functionalisations of C-H bonds.. Green Chemistry, 2013, 15 (1), pp.67-71. ⟨10.1039/c2gc36222h⟩. ⟨hal-00809459⟩