Are ARID5B and IKZF1 polymorphisms also associated with childhood acute myeloblastic leukemia: the ESCALE study (SFCE)?

Jérémie Rudant , Laurent Orsi , Audrey Bonaventure , Stéphanie Goujon-Bellec , Eve Corda , André Baruchel , Yves Bertrand , Brigitte Nelken , Alain Robert , Gérard Michel , Nicolas Sirvent , Pascal Chastagner (1) , Stéphane Ducassou , Xavier Rialland , Denis Hémon , Guy Leverger (2) , Jacqueline Clavel

1 CRAN - Centre de Recherche en Automatique de Nancy
2 CHU Trousseau [APHP]

Of the average 470 new cases of acute leukemia (AL) registered annually in France among children aged <15 years,1 |[sim]|90 are cases of acute myeloblastic leukemia (AML). Down|[rsquo]|s syndrome and other inheritable predisposing diseases explain only a small proportion of AML.

Domaines: Cancer

Jérémie Rudant, Laurent Orsi, Audrey Bonaventure, Stéphanie Goujon-Bellec, Eve Corda, et al.. Are ARID5B and IKZF1 polymorphisms also associated with childhood acute myeloblastic leukemia: the ESCALE study (SFCE)?. Leukemia, 2013, 27 (3), pp.746-748. ⟨10.1038/leu.2012.244⟩. ⟨hal-00765674⟩