Insulated gold micro singularities for high density cell trapping based on dielectrophoresis

Abstract : Dielectrophoresis (DEP) is broadly used in microfluidic systems for the cell therapies or medical diagnostics [1] because of its capability to handle and sort biological cells [2,3]. In this paper, a new method to trap cells on-chip with high density arraying capabilities is proposed. The principle is based on the use of metallic singularities arrayed within the flowing channel of the biochip. These singularities, even at a floating potential, induce a non uniform electrical field within the structure, responsible of a strong DEP force applied to cells. Indeed, we will demonstrate in the paper that metallic singularities generate stronger DEP forces, compared to more conventional methods where micro-dots of insulating material are arrayed to produce the electrical field traps. [4]. To the best of our knowledge, we report here the first successful use of such floating potential metallic singularities to trap cells
Complete list of metadatas

Cited literature [2 references]  Display  Hide  Download
Contributor : Bruno Le Pioufle <>
Submitted on : Tuesday, February 19, 2013 - 8:57:14 PM
Last modification on : Wednesday, May 22, 2019 - 1:33:02 AM
Long-term archiving on : Monday, May 20, 2013 - 4:00:14 AM


Files produced by the author(s)


  • HAL Id : hal-00739186, version 1


Claire Dalmay, Olivier Français, Frédéric Subra, Bruno Le Pioufle. Insulated gold micro singularities for high density cell trapping based on dielectrophoresis. Nanobiotech, 2011, Montreux, Switzerland. ⟨hal-00739186⟩



Record views


Files downloads