Positioning and orientation of adherent cells in a microfluidic chip using the micro patterning of a parylen-C-film

Abstract : A new biochip for adherent cell trapping using micro patterned parylene-C is presented. We demonstrate the ability of micro patterned parylene-C films to provide an efficient positioning and orientation of cells. It is also possible to fix one cell separate from the others which may be crucial in the development of biodevices for the single-cell analysis. The developed method does not require any chemical treatment of either cells or surface attachment and is suitable to be integrated into a microfluidic system.
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Claire Dalmay, Yung-Yung Lai, Laurent Griscom, Olivier Français, Bruno Le Pioufle, et al.. Positioning and orientation of adherent cells in a microfluidic chip using the micro patterning of a parylen-C-film. biodevices, 2011, Rome, Italy. ⟨hal-00739185⟩

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