Design of a well-defined, silica-supported chiral Zn scaffold for enantioselective catalysis.

Jérémy Ternel (1) , Laurent Delevoye (1) , Francine Agbossou-Niedercorn (1) , Thierry Roisnel (2) , Régis M. Gauvin (1) , Christophe M. Thomas (3)

1 UCCS - Unité de Catalyse et Chimie du Solide - UMR 8181
2 ISCR - Institut des Sciences Chimiques de Rennes
3 Laboratoire Charles Friedel

New compound Zn[(S,S)-iPr-pybox](Et)(2) (1) was fully characterized, including by X-ray diffraction structural studies. Its grafting onto partially dehydroxylated silica affords material 2, which bears well-defined chiral ([triple bond]SiO)Zn[(S,S)-iPr-pybox](Et) sites. Hybrid material 2 displays significantly better catalytic performances than 1 in enantioselective silylcyanation, thus demonstrating a beneficial grafting effect.

Domaines: Catalyse

Jérémy Ternel, Laurent Delevoye, Francine Agbossou-Niedercorn, Thierry Roisnel, Régis M. Gauvin, et al.. Design of a well-defined, silica-supported chiral Zn scaffold for enantioselective catalysis.. Dalton Transactions, 2010, 39 (16), pp.3802-4. ⟨10.1039/c003552c⟩. ⟨hal-00738775⟩