Trapping of Magnetically‐Labelled Liposomes on Flat Micro‐Patterned Hard Magnetic Films
Résumé
In this paper, we describe the use of Giant Unilamellar Vesicles (GUV) as cellular models to illustrate the possibility to trap magnetically-marked cells on a flat micro-patterned hard magnetic film by magnetophoresis. GUV can encapsulate nano- or micro-functional objects during the electroformation process and the amount of magnetic material incorporated can be controlled by regulating the concentration of magnetic nanoparticles in the electroformation buffer. The micromagnet arrays described in this paper are capable of generating high magnetic field gradients, which favors attraction of the magnetic GUV. These flat magnetic microstructures are obtained using the recently developed thermo-magnetic patterning technique (TMP).