Breather-mediated energy transfer in proteins

Abstract : In this paper we investigate how energy is redistributed across protein structures, following localized kicks, within the framework of a nonlinear network model. We show that energy is directed most of the times to a few specific sites, systematically within the stiffest regions. This effect is sharpened as the energy of the kicks is increased, with fractions of transferred energy as high as 70% already for kicks above [20] kcal/mol. Remarkably, we show that such site-selective, high-yield transfers mark the spontaneous formation of spatially localized, time-periodic vibrations at the target sites, acting as efficient energy-collecting centers. A comparison of our simulations with a previously developed theory reveals that such energy-pinning modes are discrete breathers, able to carry energy across the structure in an quasi-coherent fashion by jumping from site to site.
Document type :
Journal articles
Complete list of metadatas

https://hal.archives-ouvertes.fr/hal-00720691
Contributor : Isabelle Frapart <>
Submitted on : Wednesday, July 25, 2012 - 2:05:32 PM
Last modification on : Wednesday, June 27, 2018 - 8:24:02 AM

Identifiers

  • HAL Id : hal-00720691, version 1

Collections

Citation

Francesco Piazza, Yves-Henri Sanejouand. Breather-mediated energy transfer in proteins. Discrete and Continuous Dynamical Systems - Series S, American Institute of Mathematical Sciences, 2011, 4 (5), pp.1247-1266. ⟨hal-00720691⟩

Share

Metrics

Record views

106