A rhenium tris-carbonyl derivative as a single core multimodal probe for imaging (SCoMPI) combining infrared and luminescent properties.

Sylvain Clède , François Lambert (1, 2) , Christophe Sandt , Zoher Gueroui , Matthieu Réfrégiers , Marie-Aude Plamont , Paul Dumas (3) , Anne Vessières (4) , Clotilde Policar (1, 2)

1 ICMMO - Institut de Chimie Moléculaire et des Matériaux d'Orsay
2 UPMC - Université Pierre et Marie Curie - Paris 6
3 SSOLEIL - Synchrotron SOLEIL
4 CBCM - Chimie et biochimie des complexes moléculaires

A rhenium tris-carbonyl derivative has been designed to couple infrared and luminescent detection in cells. Both spectroscopies are consistent with one another; they point out the reliability of the present SCoMPI (for Single Core Multimodal Probe for Imaging) for bimodal imaging and unambiguously indicate a localization at the Golgi apparatus in MDA-MB-231 breast cancer cells.

Domaines: Chimie organique

Sylvain Clède, François Lambert, Christophe Sandt, Zoher Gueroui, Matthieu Réfrégiers, et al.. A rhenium tris-carbonyl derivative as a single core multimodal probe for imaging (SCoMPI) combining infrared and luminescent properties.. Chemical Communications, 2012, 48 (62), pp.7729-7731. ⟨10.1039/c2cc32163g⟩. ⟨hal-00713189⟩