Spectral Clustering of Shape and Probability Prior Models for Automatic Prostate Segmentation in Ultrasound Images

Abstract : Imaging artifacts in Transrectal Ultrasound (TRUS) images and inter-patient variations in prostate shape and size challenge computer-aided automatic or semi-automatic segmentation of the prostate. In this paper, we propose to use multiple mean parametric models derived from principal component analysis (PCA) of shape and posterior probability information to segment the prostate. In contrast to traditional statistical models of shape and intensity priors, we use posterior probability of the prostate region determined from random forest classification to build, initialize and propagate our model. Multiple mean models derived from spectral clustering of combined shape and appearance parameters ensure improvement in segmentation accuracies. The proposed method achieves mean Dice similarity coefficient (DSC) value of 0.96 0.01, with a mean segmentation time of 0.67 0.02 seconds when validated with 46 images from 23 datasets in a leave-one-patient-out validation framework.
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Soumya Ghose, Jhimli Mitra, Arnau Oliver, Robert Marti, Xavier Llado, et al.. Spectral Clustering of Shape and Probability Prior Models for Automatic Prostate Segmentation in Ultrasound Images. IEEE The Engineering in Medicine and Biology Conference, Aug 2012, San Diego, United States. ⟨hal-00710953⟩

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