Rule-based modelling and tunable resolution

Russ Harmer (1, 2)

1 PPS - Preuves, Programmes et Systèmes
2 HMS - Harvard Medical School [Boston]

We investigate the use of an extension of rule-based modelling for cellular signalling to create a structured space of model variants. This enables the incremental development of rule sets that start from simple mechanisms and which, by a gradual increase in agent and rule resolution, evolve into more detailed descriptions.

Domaines: Bio-informatique [q-bio.QM]; Bio-Informatique, Biologie Systémique [q-bio.QM]; Modélisation et simulation

Russ Harmer. Rule-based modelling and tunable resolution. EPTCS, 2009, 9, pp.65-72. ⟨hal-00694488⟩