Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome

K.L. van Bueren , I. Papangeli , Francesca Rochais (1) , K. Pearce , C. Roberts , A. Calmont , D. Szumska , R.G. Kelly (1) , S. Bhattacharya (2) , P.J. Scambler

1 IBDM - Institut de Biologie du Développement de Marseille
2 NC State - North Carolina State University [Raleigh]

Mots clés: Animals; Basic Helix-Loop-Helix Transcription Factors/genetics/*metabolism; Branchial Region/*embryology/metabolism; Chromosomes/genetics; Embryo; Mammalian/metabolism; Heart/*embryology; Homeodomain Proteins/genetics/*metabolism; In Situ Hybridization; Mice; Knockout; Syndrome; Animals; Sequence Deletion; T-Box Domain Proteins/genetics/metabolism; beta-Galactosidase/genetics/metabolism; Thymus Gland/*embryology/metabolism

Domaines: Biologie cellulaire

K.L. van Bueren, I. Papangeli, Francesca Rochais, K. Pearce, C. Roberts, et al.. Hes1 expression is reduced in Tbx1 null cells and is required for the development of structures affected in 22q11 deletion syndrome. Developmental Biology, 2010, 340 (2), pp.369-80. ⟨10.1016/j.ydbio.2010.01.020⟩. ⟨hal-00505943⟩