Enhanced catalyst recovery in an aqueous copper-free Sonogashira cross-coupling reaction

Daniel Rosario-Amorin (1, 2) , Manuel Gaboyard (3) , Rodolphe Clérac (4) , Sylvain Nlate (1, 2) , Karine Heuzé (1, 2)

1 UB - Université Sciences et Technologies - Bordeaux 1
2 ISM - Institut des Sciences Moléculaires
3 Ademtech S.A.
4 CRPP - Centre de recherches Paul Pascal

We report the synthesis of a superparamagnetic nanoparticle MNP (c-Fe2O3/polymer) supported dendritic catalyst based on a bulky electron-rich phosphine Pd(II) complex. The high reactivity of this catalyst is described in a copper-free Sonogashira C–C cross-coupling reaction in water, and the significant role of surfactant additives is highlighted in the recovery study.

Mots clés: Synthesis; Catalyse; Cross-coupling reaction

Domaines: Chimie de coordination; Matériaux

Daniel Rosario-Amorin, Manuel Gaboyard, Rodolphe Clérac, Sylvain Nlate, Karine Heuzé. Enhanced catalyst recovery in an aqueous copper-free Sonogashira cross-coupling reaction. Dalton Transactions, 2011, 40, pp. 44-46. ⟨10.1039/c0dt01204a⟩. ⟨hal-00551334⟩