Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels.

Fabrice Jossinet (1) , Thomas E Ludwig (1) , Eric Westhof (1)

1 ARN - Architecture et Réactivité de l'ARN

SUMMARY: Assemble is an intuitive graphical interface to analyze, manipulate and build complex 3D RNA architectures. It provides several advanced and unique features within the framework of a semi-automated modeling process that can be performed by homology and ab initio with or without electron density maps. Those include the interactive editing of a secondary structure and a searchable, embedded library of annotated tertiary structures. Assemble helps users with performing recurrent and otherwise tedious tasks in structural RNA research. AVAILABILITY AND IMPLEMENTATION: Assemble is released under an open-source license (MIT license) and is freely available at http://bioinformatics.org/assemble. It is implemented in the Java language and runs on MacOSX, Linux and Windows operating systems.

Domaines: Biochimie, Biologie Moléculaire

Fabrice Jossinet, Thomas E Ludwig, Eric Westhof. Assemble: an interactive graphical tool to analyze and build RNA architectures at the 2D and 3D levels.. Bioinformatics, 2010, 26 (16), pp.2057-9. ⟨10.1093/bioinformatics/btq321⟩. ⟨hal-00529831⟩