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Functional and evolutionary analysis of a eukaryotic parasitic genome

Abstract : The DNA sequences of the 11 linear chromosomes of the ∼2.9 Mbp genome of Encephalitozoon cuniculi, an obligate intracellular parasite of mammals, include ∼2000 putative protein-coding genes. The compactness of this genome is associated with the length reduction of various genes. Essential functions are dependent on a minimal set of genes. Phylogenetic analysis supports the hypotheses that microsporidia are related to fungi and have retained a mitochondrion-derived organelle, the mitosome.
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Contributor : Stéphane Delmotte Connect in order to contact the contributor
Submitted on : Wednesday, October 28, 2009 - 4:58:08 PM
Last modification on : Sunday, September 25, 2022 - 3:54:51 AM

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Christian Vivarès, Manolo Gouy, F. Thomarat, G. Metenier. Functional and evolutionary analysis of a eukaryotic parasitic genome. Current Opinion in Microbiology, Elsevier, 2002, 5, pp.499-505. ⟨10.1016/S1369-5274(02)00356-9⟩. ⟨hal-00427309⟩



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