The 2008 update of the Aspergillus nidulans genome annotation: a community effort.

Jennifer Russo Wortman , Jane Mabey Gilsenan , Vinita Joardar , Jennifer Deegan , John Clutterbuck , Mikael R Andersen , David Archer , Mojca Bencina , Gerhard Braus , Pedro Coutinho , Hans von Döhren , John Doonan , Arnold J M Driessen , Pawel Durek , Eduardo Espeso , Erzsébet Fekete , Michel Flipphi (1, 2) , Carlos Garcia Estrada , Steven Geysens , Gustavo Goldman , Piet W J de Groot , Kim Hansen , Steven D Harris , Thorsten Heinekamp , Kerstin Helmstaedt , Bernard Henrissat , Gerald Hofmann , Tim Homan , Tetsuya Horio , Hiroyuki Horiuchi , Steve James , Meriel Jones , Levente Karaffa , Zsolt Karányi , Masashi Kato , Nancy Keller , Diane E Kelly , Jan a K W Kiel , Jung-Mi Kim , Ida J van Der Klei , Frans M Klis , Andriy Kovalchuk , Nada Krasevec , Christian P Kubicek , Bo Liu , Andrew Maccabe , Vera Meyer , Pete Mirabito , Márton Miskei , Magdalena Mos , Jonathan Mullins , David R Nelson , Jens Nielsen , Berl R Oakley , Stephen A Osmani , Tiina Pakula , Andrzej Paszewski , Ian T. Paulsen , Sebastian Pilsyk , István Pócsi , Peter J Punt , Arthur F J Ram , Qinghu Ren , Xavier Robellet (1) , Geoff Robson , Bernhard Seiboth , Piet van Solingen , Thomas Specht , Jibin Sun , Naimeh Taheri-Talesh , Norio Takeshita , Dave Ussery , Patricia A Vankuyk , Hans Visser , Peter J I van de Vondervoort , Ronald P de Vries , Jonathan Walton , Xin Xiang , Yi Xiong , an Ping Zeng , Bernd W Brandt , Michael J Cornell , Cees a M J J van den Hondel , Jacob Visser , Stephen G Oliver , Geoffrey Turner

1 IGM - Institut de génétique et microbiologie [Orsay]
2 IATA - Instituto de Agroquimica y Tecnologia de Alimentos

The identification and annotation of protein-coding genes is one of the primary goals of whole-genome sequencing projects, and the accuracy of predicting the primary protein products of gene expression is vital to the interpretation of the available data and the design of downstream functional applications. Nevertheless, the comprehensive annotation of eukaryotic genomes remains a considerable challenge. Many genomes submitted to public databases, including those of major model organisms, contain significant numbers of wrong and incomplete gene predictions. We present a community-based reannotation of the Aspergillus nidulans genome with the primary goal of increasing the number and quality of protein functional assignments through the careful review of experts in the field of fungal biology.

Domaines: Biochimie, Biologie Moléculaire; Microbiologie et Parasitologie

Jennifer Russo Wortman, Jane Mabey Gilsenan, Vinita Joardar, Jennifer Deegan, John Clutterbuck, et al.. The 2008 update of the Aspergillus nidulans genome annotation: a community effort.. Fungal Genetics and Biology, 2009, 46 Suppl 1, pp.S2-13. ⟨10.1016/j.fgb.2008.12.003⟩. ⟨hal-00418937⟩