Biological and chemical gold nanosensors based on localized surface plasmon resonance

Grégory Barbillon (1) , Jean-Louis Bijeon (1) , Jerome Plain (1) , Marc Lamy de La Chapelle (1) , Pierre-Michel Adam (1) , Pascal Royer (1)

1 LNIO - Laboratoire de Nanotechnologie et d'Instrumentation Optique

this paper, we discuss the performances of gold nanosensors based on Localized Surface Plasmon Resonance (LSPR) designed by Electron Beam Lithography (EBL) in the context of biological and chemical sensing. We demonstrate the sensitivity of our gold nanosensors by studying the influence of the concentration of 11-mercaptoundecanoic acid (MUA) on the shift of LSPR wavelength. Additionally, to study the selectivity of our nanosensors, the system Biotin/Streptavidin was used to detect very weak concentration of biomolecules. These results represent new steps for applications in chemical research and medical diagnostics.

Mots clés: localized surface plasmon resonance; nanosensor; MUA; streptavidin

Domaines: Micro et nanotechnologies/Microélectronique

Grégory Barbillon, Jean-Louis Bijeon, Jerome Plain, Marc Lamy de La Chapelle, Pierre-Michel Adam, et al.. Biological and chemical gold nanosensors based on localized surface plasmon resonance. Gold Bulletin : The journal of gold science, technology and applications , 2007, 40 (3), pp.240-244. ⟨10.1007/BF03215587⟩. ⟨hal-00416066⟩