Severe acquired toxoplasmosis caused by wild cycle of Toxoplasma gondii, French Guiana.

Bernard Carme (1) , Magalie Pierre Demar (2) , Daniel Ajzenberg (3, 4, 5) , Marie-Laure Dardé (3, 4, 5)

1 Laboratoire Hospitalo-Universitaire de Parasitologie-Mycologie
2 EA 3593 - Unité de Maladies infectieuses et tropicales-Hygiène hospitalière
3 UNILIM - Université de Limoges
4 NETEC - Neuroépidémiologie Tropicale et Comparée
5 CNR Toxoplasmose-Toxoplasma BRC - Centre National de Référence (CNR) Toxoplasmose/Toxoplasma Biological Resource Center (BRC)

From 1998 through 2006, 44 cases of severe primary toxoplasmosis were observed in French Guiana in immunocompetent adults. Toxoplasma gondii isolates exhibited an atypical multilocus genotype. Severe disease in humans may result from poor host adaptation to neotropical zoonotic strains of T. gondii circulating in a forest-based cycle.

Domaines: Santé publique et épidémiologie

Bernard Carme, Magalie Pierre Demar, Daniel Ajzenberg, Marie-Laure Dardé. Severe acquired toxoplasmosis caused by wild cycle of Toxoplasma gondii, French Guiana.. Emerging Infectious Diseases, 2009, 15 (4), pp.656-8. ⟨hal-00406549⟩