Magnetic hyperthermia with biphasic gel of La_1−xSr_xMnO₃ and maghemite

Nand Kishore Prasad (1, 2) , Lucile Hardel (3) , Etienne Duguet (3) , Dhirendra Bahadur (1, 4)

1 Department of Metallurgical Engineering and Materials Science
2 Department of Metallurgical Engineering
3 ICMCB - Institut de Chimie de la Matière Condensée de Bordeaux
4 Centre for Research in Nanotechnology & Science

Magnetic hyperthermia experiments were carried out using a biphasic gel of La_1−xSr_xMnO₃(LSMO) and γ-Al_0.07 Fe_1.93O₃ with an AC magnetic field of amplitude 88 mT and a frequency of 108 kHz. Specific absorption rate (SAR) increases with the increased ratio of Al-substituted maghemite. The T_max value for the gels prepared by the mixture of LSMO and Al-substituted maghemite can be adjusted to suit therapeutic temperature. The time required to reach optimum temperature decreased with the increased ratio of later. Such biphasic gel could be very useful for magnetic hyperthermia with in vivo control of temperature.

Mots clés: Magnetic nanoparticle; Magnetic hyperthermia; Specific absorption rate; Maghemite; Manganite and Curie temperature

Domaines: Matériaux

Nand Kishore Prasad, Lucile Hardel, Etienne Duguet, Dhirendra Bahadur. Magnetic hyperthermia with biphasic gel of La_1−xSr_xMnO₃ and maghemite. Journal of Magnetism and Magnetic Materials, 2009, 321 (10), pp.1490-1492. ⟨10.1016/j.jmmm.2009.02.063⟩. ⟨hal-00378362⟩