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Mélange et hybridation dans les biopuces

Abstract : The purpose of modern microfluidics systems used in DNA biochips is to be able to process very small samples. In order to maximize the hybridization kinetics of DNA targets, the use of in situ macroscale mixing methods may be necessary. A complete mathematical modelling of a typical biochip design has been derived, together with a dimensional analysis, displaying the different characteristic times corresponding to each physical phenomenon. This approach, which has been completed with a numerical resolution of the problem, emphasises on the various critical parameters.
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https://hal.archives-ouvertes.fr/hal-00199295
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  • HAL Id : hal-00199295, version 1

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Ernest Galbrun, Alain Glière, Jean-Luc Achard. Mélange et hybridation dans les biopuces. 17e Congrès Français de Mécanique (CFM 2005), Aug 2005, Troyes, France. ⟨hal-00199295⟩

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