Wave Emission from Heterogeneities Opens a Way to Controlling Chaos in the Heart

Alain Pumir (1) , V. Nikolski (2) , M. Horning (3) , A. Isomura (3) , K. Agladze (3) , K. Yoshikawa (3) , R. Gilmour (4) , E. Bodenschatz (5) , Valentin Krinsky (1, 3)

1 INLN - Institut Non Linéaire de Nice Sophia-Antipolis
2 Medtronic SNT
3 Department of Applied Mathematics and Physics
4 Dpt of Biomedical Sciences
5 MPIDS - Max Planck Institute for Dynamics and Self-Organization

The effectiveness of chaos control in large systems increases with the number of control sites. We find that electric field induced wave emission from heterogeneities (WEH) in the heart gives a unique opportunity to have as many control sites as needed. The number of pacing sites grows with the amplitude of the electric field. We demonstrate that WEH has important advantages over methods used in clinics, and opens a new way to manipulate vortices in experiments, and potentially to radically improve the clinical methods of chaos control in the heart.

Mots clés: Cardiac dynamics; Electric field effects on biomolecules; cells and higher organisms

Domaines: Adaptation et Systèmes auto-organisés [nlin.AO]

Alain Pumir, V. Nikolski, M. Horning, A. Isomura, K. Agladze, et al.. Wave Emission from Heterogeneities Opens a Way to Controlling Chaos in the Heart. Physical Review Letters, 2007, pp.208101. ⟨10.1103/PhysRevLett.99.208101⟩. ⟨hal-00193840⟩