Fluorescence lifetime imaging microscopy for in situ observation of the nanocrystallization of rubrene in a micro fluidic set up

Serge Desportes (1, 2) , Zenji Yatabe (1, 2) , Sébastien Baumlin (1) , Valérie Génot (1, 2) , Jean-Pierre Lefèvre , Hideharu Ushiki (3) , Jacques Delaire (1) , Robert Bernard Pansu (1, 2)

1 PPSM - Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires
2 IDA - Institut d'Alembert
3 Laboratory of Molecular Dynamics and Complex Chemical Physics

A 3D hydrodynamic focusing microreactor was used to observe the in situ nanocrystallization of rubrene by fluorescence lifetime imaging (FLIM). The crystallization is achieved by a precipitation method based on the addition of a non-solvent. The rubrene solution flows from a capillary and is squeezed in 3D by two side flows containing water. The principle of the 3D hydrodynamic focusing is detailed; this device allows to follow in situ the crystallization process in less that 5 ms. Moreover, different experiment have demonstrated the possibility of quantifying the dynamics of the crystallization process.

Mots clés: microfluidic; FLIM; Cristallisation; 3D Hydrodynamic focusing

Domaines: Chimie théorique et/ou physique; Génie chimique

Serge Desportes, Zenji Yatabe, Sébastien Baumlin, Valérie Génot, Jean-Pierre Lefèvre, et al.. Fluorescence lifetime imaging microscopy for in situ observation of the nanocrystallization of rubrene in a micro fluidic set up. Chemical Physics Letters, 2007, 46, pp.212-6. ⟨hal-00189042⟩